Authors
Dopsaj Violeta, Faculty of Pharmacy, University of Belgrade
Veljković Milena, Institute of Nuclear Sciences Vinča
Veljković Nevena, Institute of Nuclear Sciences Vinča
Abstract
It is shown in this article that physical exercise can significantly contribute to prevention and suppression of disease development in HIV infected individuals. The findings presented in this review show that physical exercise induces production of anti-vasoactive intestinal peptide (anti-VIP) antibodies in the sera of both HIV infected and non-infected individuals by increasing the level of VIP protein. Negative correlation observed between progression of HIV disease and level of anti-VIP antibodies titer in HIV infected patients reflects decrease in amount of HIV particles present in the circulation, which occur as a consequence of the anti-VIP antibodies’ high affinity for HIV gp120 antigen. Taking into account deficiencies of currant medical therapies for AIDS and lack of prospective vaccine, aerobic physical exercise can be considered as highly promising and widely accessible non-toxic therapy for AIDS.
Keywords
HIV, vasoactive intestinal peptide (VIP), cancer, physical exercise
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